No comments about NMR Quantum Information Processing.

No comments about Process Analytical Technology: Spectroscopic Tools and Implementation Strategies for the Chemical and Pharmaceutical Industries.

3 comments about Protein Sequencing and Identification Using Tandem Mass Spectrometry.

1. Michael Kinter has presented the topic in a scientific yet enjoyable format. I found the information to be extremely interesting and beneficial in my laboratory. Lets face it folks this isn't the easiest nor most interesting topic to write about. Job well done DR. Kinter. I only have one criticism, there should have been more photos and illustrations. Get your copies quick this will no doubt be on the NewYork times best seller list before long.



2. I'm not a bench chemist, but I needed a quick survey of how mass spectroscopy is used in handling proteins and other big biomolecules. This book was it.
   
   Although brief, it is thorough and well-organized. The first two chapters are mostly an introduction. Chapter 1 states the problem being solved. The next chapter briefly introduces older technologies, including chemical techiques and 60s-80s mass spec technique. The next two chapters summarize modern mass spec hardware, then start to show how proteins behave in the environment inside the instrument. That gives the fundamentals of protein sequencing: how the molecules break down, and how the fragments help recreate the molecule. The authors go through a few examples in detail, starting from a mass spectrogram and moving forward to sequence. I was especially impressed by the examples that fail. Mass spec analysis is not a magic wand for producing sequences, it is a deductive process, and can not complete an analysis when clues are missing or ambiguous.
   
   The next three chapters are not about mass spec directly. Instead, they discuss how samples are prepared for analysis. This includes the clearest, most informative description of gel electrophoresis that I've seen, along with features of gel chemistry that do or do not interfere with mass spec measurements. This includes a discussion of protein digests, enzymatically produced fragments, and their place in analysis. I would have liked a little more discussion about combining information from digests produced by different enzymes, but no book can cover everything.
   
   The last three chapters extend the discussion of analysis, working upwards from fragments to complete protein sequences. The three chapters respectively address three topics: using standard internet databases for recognizing fragments of known proteins, using combinations of strategies to analyze novel proteins, and using mass spec to identify post-translational modifications. That last one suffers from brevity; perhaps it was only meant to define a problem that deserves a whole book of its own.
   
   Despite its throughness, the authors resist the urge for boggling detail. They present detail up to the point needed for understanding the mechanism and meaning of their topics, then stop. Lots of other writing would benefit from that kind of restraint.
   
   I came away from this book well-informed, and ready to address specific topics in greater detail. That was exactly what I wanted. I recommend this book very highly.
   
   //wiredweird



3. Ao ler esse livro pude perceber que existe variadas técnicas que auxiliam na interpretação dos espectros de massas. A obra descreve os métodos de ionização e a formação dos íons moleculares e quasi-moleculares em cada um desses métodos. O livro tras a interpretação da distribuição de isótopos nas amostras, a identificação dos "parent ions", "base piks" e a distribuição das cargas durante a interpretação dos espectros. A interpretação de sequências de aminoácidos durante a análise de peptídios é rica em dicas, tabelas e exercícios resolvidos. De forma clara é possível entender a lógica por tras da formação das séries de íons A, B, C, X, Y e Z tão importantes durante a identificação da estrutura primária dos peptídeos. Se você pretende trabalhar com a identidficação de compostos de origem protéica utilizando espectrometria de massas, esse deverá ser seu livro de cabeceira!

1 comments about Applied Spectroscopy.

1. "In short, the wide variety of topics covered means no matter what the reader's background, much of the book will cover spectroscopy related subjects that are unfamiliar. This book gives a very useful overview of spectroscopy that will allow the reader to learn methods for doing things in other spectroscopic areas that could be potentially applied to his own. Highly recommended" H. Mark in Spectroscopy Magazine Showcase, March 1999

No comments about Infrared and Raman Characteristic Group Frequencies: Tables and Charts.

2 comments about Electron Paramagnetic Resonance: Elementary Theory and Practical Applications.

1. Electron paramagnetic resonance is a fairly complicated experimental technique, and the task of writing a textbook on this method is extremely challenging. This particular book is written by experienced scientists and covers all major modifications of EPR, as well as extensive bibliography. However, the presentation of the material could be much, much better. I found it very hard to follow the authors mostly because the systematics in presentation, from full explanation of simple things to more complicated ones, is lacking almost completely. Sometimes I even had a strange feeling that subsections of the book were written independently and were just put next to each other in the final manuscript, so different is their writing style, and so weakly they are related to each other. Unfortunately, there are not so many books on EPR published recently which are available at bookstores, so the readers do not have a lot of choice...



2. As a graduate student at Caltech, I first started learning about EPR from the first edition of this book. The first edition (much slimmer) was not perfect, and I found useful complementary information in the works of Poole and Baird, but I noticed that I kept returning to Weil and Bolton for answers to my most fundamental questions. The appendices including lucid treatments on instrumental design and the relevant quantum mechanics were particularly useful in my overall understanding of the theory and practice of EPR. In the newest edition, the subject is given an even broader overview, with clear discussions of modern techniques. The best of the bunch. I also recommend Poole's _Electron Spin Resonance: A Comprehensive Treatise on Experimental Techniques_, Bersohn Baird's _Electron Paramagnetic Resonance_, and the _Handbook of Electron Spin Resonance_, edited by Poole and Farach.

No comments about Remote Sensing of Landscapes with Spectral Images: A Physical Modeling Approach (Topics in Remote Sensing).

1 comments about Liquid Chromatography Mass Spectrometry: An Introduction (Analytical Techniques in the Sciences (AnTs) *).

1. This book is very fundamental. For someone with little knowledge about HPLC-MS, this is the right book for him/her. IF you want to learn LC/MS, start with this book.

2 comments about Handbook of Laser-Induced Breakdown Spectroscopy.

1. I just read The Handbook of Laser-Induced Breakdown Spectroscopy straight through in one sitting - it is a wonderful book that will be useful for those just starting in LIBS or those specialists needing a concise summary of a particular area with a current set of references.
   
   As a LIBS researcher (U.C. San Diego) and practitioner (Photon Machines, Inc.), my hat is off to Dave Cremers and Lee Radziemski for a terrific contribution. If you're interested in LIBS, I recommend this book!



2. I also happened to read the entire book in one sitting :) Being relatively new to LIBS, I found the book very interesting and helpful in understanding its various facets, more importantly the potential developments in the field of LIBS.

No comments about Even Electron Mass Spectrometry with Biomolecule Applications.