5 comments about Textbook of Biochemistry with Clinical Correlations.

1. We used this book teaching first year medical school biochemistry. The clinical correlations are well done, but the real strengh of the book lies in the sections on metabolic interrelationships. It is often confusing to the medical student to learn a pathway, and the the metabolic controls of the pathway, and then the added complexity that this system works differently in different tissues. This physiological complexity (which is the layer of integration where diagnosis really happens) is tackled head on in the first few chapters. This helps keep the student oriented to the system (the patient) and not get totally lost in the trees of enzyme names and co-factors.
   
   I wish this book had been around when I went through medical school.
   
   duke out



2. I expected better from a 6th edition medical textbook. There are still grammatical and sentence errors that need to be corrected, and we have found multiple diagram problems throughout the book. The sentences can be poorly worded at times, and the book occassionally makes leaps in thought that are difficult to follow. It does contain a large amount of information, which is good, but the presentation of that information definitely needs to be further refined.



3. Senior in college,
   double major Biology and Chemistry.
   This is the worst book I have ever used.
   Two brief examples..
   looking for a figure? On the previous (or next) page or 100pages further down the book.
   Thought Marcel Proust could write endless sentences? Hold on! devlin can spend four to five lines, with "bold term" to explain something you won't understand the 10th time around.
   Don't waste your time, don't waste your money....stay away from this mess of a book.



4. I had to use this book for my Biochemistry class. My major is Nutrition & Dietetics, and I already graduated. This book is just awful. Like someone else wrote, if you need to find a term or a figure, you have to look in almost the whole book, and you may still won't understand what you were looking for, or even worse, you'll get more confused. Devlin finds the hardest way to explain an easy term or fact you can explain a lot easier. This is just not worth it. Do not buy this book, there are other books a lot better.



5. I wanted to get a textbook that allows me to get up to speed again with mammalian biochemistry and I bought this book in preference to more general textbooks. And on the whole I am impressed - the writing and the diagrams are clear and accurate. There is one issue however that has made a serious black mark: units. I would expect a modern textbook to use SI units throughout. The problem here is that the book skips between Calories and Joules almost at random depending upon the particular author involved. The chapter on Bioenergetics gloriously uses both - but in different parts of the chapter (for example Free-Energy Change for hexokinase is in kcals whereas the section on Free-Energy Changes in redox reactions is in joules! - without the other unit in both cases). I have an elderly copy of Lehninger from the 1970's that exclusively uses SI units and so to see a modern (2005) book still using Calories is deeply disappointing. Yes it's an irritant (even I can convert between joules and calories - 4.18) and shouldn't detract from the book but thats not the point. It just shouldn't happen and it reflects badly on the general editor

4 comments about Laboratory Manual for Principles of General Chemistry.

1. It is a typical boring and verbose, but yet comlete and unclear, lab instructions. You wont have a choice so just buy it.



2. This lab manual is the one required for my chemistry lab class at a much better price than the school offered.



3. The item was in brand new condition as described and shiiping was also fast...though price was a bit high but it worth



4. Great seller! Item was shipped FAST! Exactly as described in brand new condition. Thank You!

No comments about Clincial Chemistry: A Laboratory Perspective.

5 comments about The Organic Chemistry of Drug Design and Drug Action, Second Edition.

1. This book is very good introduction in the major aspects of the chemistry of the drugs. It explains with good schemes the reactions of drugs and others important mechanisms. The book is scientifically well written and enjouyable to read. The graphic images of molecules integrate well with the written aspects of book. Book covers major areas of pharmaceutical drug research, integrates the chemical and pharmacological aspects of drugs, and discusses the essentials of drug activity and mechanisms.



2. There is a new considerably expanded and updated edition available of Silverman's already classic text as of Jan/04. ISBN is 0-12-643732-7. Check it out... price is comparable to the earlier edition.



3. This book is fantastic and covers a broad range of topics that fall into the category of rational drug design. The book goes in depth into topics dealing with each important aspect of how drugs are discovered and modified to produce better drugs: from effects of chirality to electronic effects. The structure of drugs, at the molecular level are covered in detail, reflecting every major aspect of drug structure. Then, interaction between drug (ligand) and enzyme, at the molecular level are covered.
   
   In my estimation, to benefit most from this book, the reader should have a working knowledge of organic chemistry and biochemistry (at least protein secondary and tertiary structure).



4. This is probably the best book of its kind in the vast and multidisciplinary field of drug design and action. Richard Silverman is an acclaimed chemistry Professor at Northwestern University, and in this book, he provides the most comprehensive and lucid exposition of the chemical basis of drug action that I have seen. No matter how complicated biological systems and their interactions are, at the basic level, it's all chemistry, and mostly organic chemistry. An organic chemist will find this book extremely illuminating in a way that would not have been made clear through his traditional education.
   The book opens with a short but clear discussion of drug discovery, combinatorial chemistry, and clinical testing and trials. Then it leads the reader through a variety of enzyme catalyzed reactions, with examples of major drugs studded all the way. Silverman shows us how nature is the master organic chemist, employing the familiar reactions of chemistry in an unsurpassed way. The chapter on enzyme inhibition is long and detailed, and it's breathtaking. Which is important because almost all major drugs act by inhibiting enzymes. The examples which Silverman chooses to illustrate are both important (including many bestselling anti-cancer, anti-viral, and antibiotic drugs to name a few), as well as very interesting. The last parts of the book deal with DNA binding drugs, and with pathways of drug metabolism and excretion. Along all the way, the emphasis is on the chemical reactions that drugs undergo, which after all is what controls their properties. The lucidity of the book is such that a beginning graduate well-versed with the basic principles of general and organic chemistry can easily understand all the contents.
   This book is so interesting and illuminating that it's one of the very few academic books which I have actually read from the first to the last page, with every word in between. In fact, it even makes great bedside reading! Truly a must-have book for all chemists and biologists of every kind, interested in how drugs work.



5. The book is great for understanding the title subject. But it has too many references which distracts the reader. Also, many times, the corresponding picture of a particular topic covered is not in the same page as the topic. This requires going back and forth between pages. The problems at the end of each chapter are really good and checks the understanding of the subject thoroughly.

5 comments about Name Reactions: A Collection of Detailed Reaction Mechanisms.

1. Basically, all this book does is draw mechanisms for a whole bunch of name reactions. It doesn't really tell you all that much and only gives one example (for which the mechanism is drawn out)or each. Definately not recomended if you know how to push arrows and write a mechanism. Not at all what I was expecting.



2. This book is fantastic! It has a complete set of every important named reaction with its respective mechanism and literature references. The simple layout makes this book very user friendly. The mechanisms are easy to follow and the references are very useful making this book excellent for use at any level from undergraduate to graduate and beyond. This book is a definite must have for anyone studying advanced organic chemistry, as it is the named reactions bible.



3. this book is a really great resource for organic chemists. it has all the main name reactions in alphabetical order, and does a good job showing not only the overall reaction, but also the step-by-step mechanism as well. it also has references listed for each reaction, for further clarification. i recommend it for any organic chemist as part of their library.



4. This book is nice for writing the basics of mechanism. There are some other books available in market. But I will recommend this book because they are short and concise. This third edition is more or less similar to second edition.



5. i received the book in good condition.
   The book is very valuable for any org. chemist,be it Acadamic or Industrial.we have the old edition also. I use it to train the youngsters.
   worth to buy.

1 comments about Chemical Principles in the Laboratory (Brooks/Cole Laboratory Series for General Chemistry).

1. This book uses removable pages as prelabs which were very good in giving a conceptual idea of the experiments before they were done. Also, there are good flowcharts, equations for every step of the reactions, and formulas to help do the problems. All data that needs to be recorded is clearly mentioned in a form format.

No comments about Veterinary Hematology and Clinical Chemistry: Text and Clinical Case Presentations Set.

5 comments about Chemical Magic.

1. This text is a lot of fun, a rapid-fire compilation of visually interesting experiments. *However* it is out-of-date on safety. Despite a recent revision the text appears unaware of the great danger posed by materials such as carbon tetrachloride (a chemical which has since the 60's been all but banned), mercury, benzene, phosphorous, thermite, etc. To say "be careful" is not enough when talking to a lay audience. Please be cautious, the experiments may sound thrilling but the harm can be nasty and permanent.



2. Each experiment first explains the "action" or the effect intended to produce. Secondly, necessary elements are listed along with their appropriate quantities. Thirdly, a very fortunate addendum to each experiment explains why the reaction occurred and how it did. Finally, most experiements are augmented by a primitive diagram, whose descriptive efforts vary according the action(s) of the chemist, but nevertheless aid the reader with some significance to visualize where certain items should be oriented.
   Anyone interested in this book will understand it is not for anarchy or extremely plexiform experiments to uncover the human genome. Mad scientists, this book is unfortunately not for you, but anyone intrigued by paradoxical chemical experiments, such as fire submerged in water, a burning bush that is not consumed by its flames, and other such fascinating elements, will be pleased with its contents.
   These experiments usually do not require manifold ingredients so they are ideal for high-school chemistry classes, introductory college chemistry, or entertainment during a meal. A waiter who can perform such legerdemain at events will not remain a waiter long, and those of you who are addicted to gambling and teasing friends certain things are impossible will immediately recognize the value of this book.
   I have rated this book 4-star primarily because the majority of the experiments are prosaic or have no genuine purpose to belong the the publishment. However, those experiments that really are "chemical magic" scintillate like stars amid the black heavens, illuminating their observers and imparting them joy at a further comprehension of experimental chemistry.



3. This book gives lots of chemical demonstration ideas. However, some are entirely too dangerous to do. You must use a lot of common sense when considering doing any of these demonstrations. Some are not safe at all. Mercury and CCl4 are EPA regulated. It's not advisable to put ethanol in your mouth to spit out in front of students... This only demonstrates bad lab techniques. Make sure you do the first experiment in the book outside or in a fume hood. It releases a strong odor and an acid vapor. Definitely not something you want your students breathing!



4. This book reminds me of how we've gone a society of educational discovers to one that irrationally sees harm in a simple chemistry set.
   
   There are experiments that I've heard told and retold, some of which I seriously attributed to exaggeration. For instance, a glass beaker submerged in a liquid that has the same refractive index as glass, rendering the beaker completely invisible. Or, another, volumes of smoke made as if by magic.
   
   It turns out they're all in here! Don't let the physical size fool you, because this book is chalked full of some of the most amazing and impressive chemistry experiments you've ever seen.
   
   The problem, however, is that the typical home reader won't be able to get their hands on these chemicals anymore. So while you can read about them, you can't conduct the experiments yourself.
   
   About the only people who'd get practical benefit out of this book would be college chemistry professors who want to lure students into the profession. This would be an impressive way to do it.



5. Excellent book !. For many chemistry students it has been the first book in order to see chemistry as a beautiful and funny science. Dr. L. A. Ford is no longer living but this masterpiece will remain for many years as an element for motivation in teaching and learning chemistry.

5 comments about Advanced Organic Chemistry: Part A: Structure and Mechanisms (Advanced Organic Chemistry / Part A: Structure and Mechanisms).

1. It is now more than a month after I was supposed to receive this book and I have not gotten it yet, what the hell is going on.



2. This book is written at the undergraduate level. The figures are a joke. It's a paperback and will fall apart. If you are in graduate school; buy the text by Anslyn & Dougherty instead. It is a nice hard bound book, durable & weighs a ton. Its worth the money and the weight in your backpack.



3. This text is good for an advanced undergraduate course. It is a pretty good reference, with two major problems:
   
   1) The book is a flimsy paperback. Other paperbacks I have can withstand usage just fine, but after 1 month the text was in two pieces. It feel apart at the binding. I never even brought it to class, it sat on the bookshelf and fell apart after twice a week readings.
   
   2) The solutions are presented as references to journal articles. I am not too shy of searching for articles, but when you are in a crunch it would be nice to not have to search through 10 pages of tangential information to find the one data or conclusion you need in order to verify the accuracy of your work.
   
   Besides for that, it worked just fine for my advanced undergrad course in physical organic chemistry. I did have to make frequent references to other sources for more in-depth information, but when study time came it worked better than the myriad organic texts available at my library.



4. I have been using this book since the first edition, in my postgraduation courses and each time, it is better. The 5th edition introduced aspects that we awere longing for, like, for example, new achievements in the area of aromaticity and improvements in the first chapter. The best improvement was attached to problems solving (despite being not so friendly) and 3D figures. A CD should be added to the next edition.



5. Everyone in the world of organic chemistry knows of Dr. Carey and the great author and chemist he is. Hardly anyone could compare with the way he slides from subject to subject, explaining in detail and ease subjects that can be rather difficult to grasp. However, his method, because of his complete understanding of the subject matter is amazing. Often I wish I had had him for an instructor for at least one course in organic or any other for that matter. It is his ability to break down difficult concepts, and introduce them in logical and orderly fashion as to make that same difficult concept... much more easy to understand. If you are thinking about graduate school, or even want to make better grades in your soph-jr 2 semester organic chem class, use this book. It will help you understand some of the topics your "quick course" book leaves out! I cannot recommend this book high enough. guyairey

5 comments about Advanced Organic Chemistry: Part B: Reaction and Synthesis (Advanced Organic Chemistry / Part B: Reactions and Synthesis).

1. This fourth edition has no big difference with the new fifth release. However, the price is only half. That is a good purchase for me.



2. This book is not for introductory organic students. It is a condensed review with some explanation for a huge number of synthetically useful organic reactions. It explains exactly what it needs to, with diagrams when necessary. This book has been extremely useful in my graduate level organic classes.



3. many thanks for your that effort , the book is good and come to me so fast



4. This is probably the most comprehensive text book available for Organic Chemistry, Develops largely on the Part A of the book. So for a complete understanding you need to possess the Part A of the book. Largely covers the topic of Synthesis and Reactions which is an important part of the Graduate education in Organic Chemistry. Earlier editions of the book cover the same material and are almost as good as this one but each topic in this edition builds up with a different approach of Computational and Theoretical Chemistry.
   The references provided in each chapter ensure the complete and total understanding of the subject and help in the student in research.
   Overall a great book for the Graduate student in Organic Chemistry.



5. This review is specifically meant to refer to the latest edition (5th ed.) of this book. The earlier editions were quite good, but the 5th edition completely misses the mark. Ordinarily, one would think that a book such as this would get better and better with each new edition. Not so with this book. For some reason, the 5th edition is loaded with mistakes.....many of these appear to be typesetting errors (e.g., atoms in the wrong place, pentavalent carbons, nonsense intermediates within reaction pathways, etc.). It is terribly disappointing. I do not know what happened at the publisher this time, but, in good conscience, they really should not have released this book the way it is. It does not appear to have been the authors' fault, but rather it was likely the fault of Springer (the publisher). This looks like an example of the mindless side of capitalism....large publishing companies who have already taken over much of their competition also have ridiculous deadlines to meet quarterly earnings goals, so they rush through the publication process and end up turning out garbage. The only way that these companies ultimately avoid getting into a heap of trouble with the FTC or other consumer advocate agencies is by issuing online addendums filled with corrections to the myriad of errors. Ask yourselves, is that why you want to buy a new book..... so that you have to download a 50-page corrections addendum to fix all of the errors that the publisher missed or opted not to correct in the first place? This sort of thing is happening more and more these days in the publishing industry, even with software. And the larger and larger these publishing companies become, the more we see it. I recommend that you DO NOT BUY the 5th edition of this book; it should have been recalled by the publisher, and everyone who bought it should have received a refund. However, if you really want to buy Carey and Sundberg's book, then buy the 4th edition used; you will be much happier. Apparently, Springer scaled back on qualified staff and/or hired a bunch of publishing flunkies sometime between the release of the 4th and 5th editions of this book.